Neurologia

Artigos em destaque

Advances in the classification and management of idiopathic inflammatory myopathies.
The Lancet. Neurology. 2025 Sep; 24(Sep):776-788. doi: 10.1016/S1474-4422(25)00233-9. pii: S1474-4422(25)00233-9. Base: PUBMED
- Atualizado em 08/09/2025

Risk of Parkinson Disease in Individuals With Autism Spectrum Disorder.
JAMA neurology. 2025 Jul; 82(Jul):687-695. doi: 10.1001/jamaneurol.2025.1284. pii: . Base: PUBMED
- Atualizado em 03/09/2025

Treatment Response to Antiseizure Medications in People With Newly Diagnosed Focal Epilepsy.
JAMA neurology. 2025 Aug; doi: 10.1001/jamaneurol.2025.2949. pii: e252949. Base: PUBMED
- Atualizado em 29/08/2025

The use of onabotulinum toxin type A and other neurotoxins for the treatment of chronic migraine: An American Headache Society survey study.
Clinical neurology and neurosurgery. 2025 Jul; 254(Jul):108960. doi: 10.1016/j.clineuro.2025.108960. pii: S0303-8467(25)00243-4. Base: PUBMED
- Atualizado em 21/08/2025

Principles for Novel Neurologic Therapeutics: An AAN Position Statement.
Neurology. 2025 Jul; 105(Jul):e213850. doi: 10.1212/WNL.0000000000213850. pii: e213850. Base: PUBMED
- Atualizado em 20/08/2025

News e Reviews

Ambient Air Pollution and the Severity of Alzheimer Disease Neuropathology.
JAMA neurology. 2025 Sep; doi: 10.1001/jamaneurol.2025.3316. pii: e253316. Base: PUBMED
- Atualizado em 17/09/2025

Neurosyphilis.
Annals of neurology. 2025 Sep; doi: 10.1002/ana.78016. pii: . Base: PUBMED
- Atualizado em 09/09/2025

Neurosyphilis in 2025.
Current opinion in neurology. 2025 Aug; 38(Aug):397-405. doi: 10.1097/WCO.0000000000001404. pii: . Base: PUBMED
- Atualizado em 08/09/2025

Association Between Consumption of Low- and No-Calorie Artificial Sweeteners and Cognitive Decline: An 8-Year Prospective Study.
Neurology. 2025 Oct; 105(Oct):e214023. doi: 10.1212/WNL.0000000000214023. pii: . Base: PUBMED
- Atualizado em 08/09/2025

Essential Tremor.
Continuum (Minneapolis, Minn.). 2025 Aug; 31(Aug):979-999. doi: 10.1212/cont.0000000000001605. pii: . Base: PUBMED
- Atualizado em 05/09/2025

Risdiplam in Presymptomatic Spinal Muscular Atrophy.
The New England journal of medicine. 2025 Aug; 393(Aug):671-682. doi: 10.1056/NEJMoa2410120. pii: . Base: PUBMED
- Atualizado em 04/09/2025

Posterior reversible encephalopathy syndrome: evolving insights in diagnosis, management, and outcomes.
The Lancet. Neurology. 2025 Sep; 24(Sep):789-800. doi: 10.1016/S1474-4422(25)00232-7. pii: S1474-4422(25)00232-7. Base: PUBMED
- Atualizado em 03/09/2025

Certolizumab pegol to prevent adverse pregnancy outcomes in patients with antiphospholipid syndrome and lupus anticoagulant (IMPACT): results of a prospective, single-arm, open-label, phase 2 trial.
Annals of the rheumatic diseases. 2025 Jun; 84(Jun):1011-1022. doi: 10.1016/j.ard.2025.02.012. pii: S0003-4967(25)00243-2. Base: PUBMED
- Atualizado em 02/09/2025

Ictal Asystole During ECT.
The journal of ECT. 2025 Aug; doi: 10.1097/YCT.0000000000001178. pii: . Base: PUBMED
- Atualizado em 01/09/2025

Safety and efficacy of apitegromab in nonambulatory type 2 or type 3 spinal muscular atrophy (SAPPHIRE): a phase 3, double-blind, randomised, placebo-controlled trial.
The Lancet. Neurology. 2025 Sep; 24(Sep):727-739. doi: 10.1016/S1474-4422(25)00225-X. pii: S1474-4422(25)00225-X. Base: PUBMED
- Atualizado em 01/09/2025

Down syndrome and Alzheimer's disease: insights into biomarkers, clinical symptoms, and pathology.
The Lancet. Neurology. 2025 Sep; 24(Sep):753-762. doi: 10.1016/S1474-4422(25)00237-6. pii: S1474-4422(25)00237-6. Base: PUBMED
- Atualizado em 01/09/2025

Psychoses of Epilepsy: Unravelling the Phenotypic and Genotypic Features.
Annals of neurology. 2025 Jul; 98(Jul):35-47. doi: 10.1002/ana.27209. pii: . Base: PUBMED
- Atualizado em 21/08/2025

Autoimmune encephalitis: recovery, residual symptoms and predictors of long-term sequelae.
Journal of neurology, neurosurgery, and psychiatry. 2025 Jul; 96(Jul):736-743. doi: 10.1136/jnnp-2024-334957. pii: . Base: PUBMED
- Atualizado em 21/08/2025

When should the effectiveness of a botulinum toxin A for chronic migraine be assessed in the face of newest International Headache Society recommendations?
Cephalalgia : an international journal of headache. 2025 Jul; 45(Jul):3331024251363268. doi: 10.1177/03331024251363268. pii: . Base: PUBMED
- Atualizado em 21/08/2025

Silent burden: recognising and managing invisible symptoms in neuromyelitis optica.
Journal of neurology, neurosurgery, and psychiatry. 2025 Jul; 96(Jul):744-752. doi: 10.1136/jnnp-2025-336041. pii: . Base: PUBMED
- Atualizado em 20/08/2025

Multiple sclerosis: advances and challenges in diagnosis.
Current opinion in neurology. 2025 Jun; 38(Jun):197-204. doi: 10.1097/WCO.0000000000001366. pii: . Base: PUBMED
- Atualizado em 20/08/2025

Brazilian Academy of Neurology recommendations for diagnosis, management, and treatment of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP).
Arquivos de neuro-psiquiatria. 2025 Jul; 83(Jul):1-19. doi: 10.1055/s-0045-1809884. pii: . Base: PUBMED
- Atualizado em 20/08/2025

Dengue encephalitis: what's new?
Current opinion in infectious diseases. 2025 Jul; doi: 10.1097/QCO.0000000000001128. pii: . Base: PUBMED
- Atualizado em 20/08/2025

Blood-based biomarkers for Alzheimer's disease: positioning document and usage recommendations from the Behavioral Neurology and Dementia Study Group of the Spanish Society of Neurology.
Neurologia. 2025 Jul; doi: 10.1016/j.nrleng.2025.07.004. pii: S2173-5808(25)00066-5. Base: PUBMED
- Atualizado em 20/08/2025

Absence of Cerebrospinal Fluid Pleocytosis in Encephalitis.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2025 Aug; 81(Aug):179-187. doi: 10.1093/cid/ciae391. pii: . Base: PUBMED
- Atualizado em 20/08/2025

Long-Term Effectiveness and Safety of Rituximab in Neuromyelitis Optica Spectrum Disorder: A 5-Year Observational Study.
CNS drugs. 2025 Jul; 39(Jul):693-705. doi: 10.1007/s40263-025-01191-7. pii: . Base: PUBMED
- Atualizado em 20/08/2025

Effects of blood pressure lowering in relation to time in acute intracerebral haemorrhage: a pooled analysis of the four INTERACT trials.
The Lancet. Neurology. 2025 Jul; 24(Jul):571-579. doi: 10.1016/S1474-4422(25)00160-7. pii: S1474-4422(25)00160-7. Base: PUBMED
- Atualizado em 20/08/2025

Alzheimer's Association Clinical Practice Guideline on the use of blood-based biomarkers in the diagnostic workup of suspected Alzheimer's disease within specialized care settings.
Alzheimer's & dementia : the journal of the Alzheimer's Association. 2025 Jul; 21(Jul):e70535. doi: 10.1002/alz.70535. pii: . Base: PUBMED
- Atualizado em 20/08/2025

Unruptured Intracranial Aneurysms.
The New England journal of medicine. 2025 Jun; 392(Jun):2357-2366. doi: 10.1056/NEJMcp2409371. pii: . Base: PUBMED
- Atualizado em 20/08/2025

Case 19-2025: A 69-Year-Old Man with Headache and Ataxia.
The New England journal of medicine. 2025 Jul; 393(Jul):176-184. doi: 10.1056/NEJMcpc2412528. pii: . Base: PUBMED
- Atualizado em 20/08/2025

Crossing the blood-brain barrier: emerging therapeutic strategies for neurological disease.
The Lancet. Neurology. 2025 Mar; 24(Mar):246-260. doi: 10.1016/S1474-4422(24)00476-9. pii: S1474-4422(24)00476-9. Base: PUBMED
- Atualizado em 20/08/2025

Drug treatment for myotonia.
The Cochrane database of systematic reviews. 2025 Apr; 4(Apr):CD004762. doi: 10.1002/14651858.CD004762.pub3. pii: CD004762. Base: PUBMED
- Atualizado em 20/08/2025

Effectiveness and Safety of Mechanical Thrombectomy in Mild Stroke due to Large-Vessel Occlusion: Insights from the ASSIST Registry.
AJNR. American journal of neuroradiology. 2025 Jun; 46(Jun):1130-1136. doi: 10.3174/ajnr.A8613. pii: . Base: PUBMED
- Atualizado em 20/08/2025

Medical management of ADHD in adults: part 1.
Drug and therapeutics bulletin. 2025 Apr; 63(Apr):74-80. doi: 10.1136/dtb.2024.000019. pii: . Base: PUBMED
- Atualizado em 20/08/2025

Comorbid Insomnia and Sleep Apnea: From Research to Clinical Practice.
Seminars in respiratory and critical care medicine. 2025 Apr; 46(Apr):113-124. doi: 10.1055/a-2591-5664. pii: . Base: PUBMED
- Atualizado em 18/08/2025

Updates on the neurological manifestations of SARS-CoV-2 infection.
Current opinion in infectious diseases. 2025 Jun; 38(Jun):234-241. doi: 10.1097/QCO.0000000000001110. pii: . Base: PUBMED
- Atualizado em 18/08/2025

Guideline, consenso e protocolo

European Academy of Neurology (EAN)/European Federation of Autonomic Societies (EFAS)/International Neuro-Urology Society (INUS) Guidelines for Practising Neurologists on the Assessment and Treatment of Neurogenic Urinary and Sexual Symptoms (NEUROGED Guidelines).
European journal of neurology. 2025 Apr; 32(Apr):e70119. doi: 10.1111/ene.70119. pii: . Base : PUBMED
- Atualizado em 20/08/2025

International Consensus Guidance for the Management of Glucocorticoid Related Complications in Neuromuscular Disease.
Muscle & nerve. 2025 Mar; 71(Mar):309-316. doi: 10.1002/mus.28328. pii: . Base : PUBMED
- Atualizado em 24/06/2025

Consensus Recommendations to Establish Reporting Standards in fMRI of Migraine: A Delphi Study.
Neurology. 2025 Mar; 104(Mar):e210235. doi: 10.1212/WNL.0000000000210235. pii: . Base : PUBMED
- Atualizado em 13/06/2025

IAPRD new consensus classification of myoclonus.
Parkinsonism & related disorders. 2025 Mar; 132(Mar):107216. doi: 10.1016/j.parkreldis.2024.107216. pii: S1353-8020(24)01228-8. Base : PUBMED
- Atualizado em 29/05/2025

High-Grade Subarachnoid Hemorrhage - Beyond Guidelines.
Neurologic clinics. 2025 Feb; 43(Feb):107-126. doi: 10.1016/j.ncl.2024.07.006. pii: S0733-8619(24)00057-4. Base : PUBMED
- Atualizado em 28/04/2025

Prevention of Episodic Migraine Headache Using Pharmacologic Treatments in Outpatient Settings: A Clinical Guideline From the American College of Physicians.
Annals of internal medicine. 2025 Feb; doi: 10.7326/ANNALS-24-01052. pii: . Base : PUBMED
- Atualizado em 13/03/2025

Acceptable performance of blood biomarker tests of amyloid pathology - recommendations from the Global CEO Initiative on Alzheimer's Disease.
Nature reviews. Neurology. 2024 Jul; 20(Jul):426-439. doi: 10.1038/s41582-024-00977-5. pii: . Base : PUBMED
- Atualizado em 28/02/2025

Management of patients with neurological diseases considering post-pandemic coronavirus disease 2019 (COVID-19) related risks and dangers - An updated European Academy of Neurology consensus statement.
European journal of neurology. 2024 Oct; 31(Oct):e16408. doi: 10.1111/ene.16408. pii: e16408. Base : PUBMED
- Atualizado em 21/01/2025

Meningioma: International Consortium on Meningiomas consensus review on scientific advances and treatment paradigms for clinicians, researchers, and patients.
Neuro-oncology. 2024 Oct; 26(Oct):1742-1780. doi: 10.1093/neuonc/noae082. pii: . Base : PUBMED
- Atualizado em 21/01/2025

International Headache Society global practice recommendations for the acute pharmacological treatment of migraine.
Cephalalgia : an international journal of headache. 2024 Aug; 44(Aug):3331024241252666. doi: 10.1177/03331024241252666. pii: . Base : PUBMED
- Atualizado em 03/01/2025

Guidelines for Seizure Prophylaxis in Adults Hospitalized with Moderate-Severe Traumatic Brain Injury: A Clinical Practice Guideline for Health Care Professionals from the Neurocritical Care Society.
Neurocritical care. 2024 Jun; 40(Jun):819-844. doi: 10.1007/s12028-023-01907-x. pii: . Base : PUBMED
- Atualizado em 22/08/2024

Management of seizures in patients with primary mitochondrial diseases: consensus statement from the InterERNs Mitochondrial Working Group.
European journal of neurology. 2024 Jul; 31(Jul):e16275. doi: 10.1111/ene.16275. pii: e16275. Base : PUBMED
- Atualizado em 21/08/2024

Expert consensus recommendations for improving and standardising the assessment of patients with generalised myasthenia gravis.
European journal of neurology. 2024 Jul; 31(Jul):e16280. doi: 10.1111/ene.16280. pii: e16280. Base : PUBMED
- Atualizado em 21/08/2024

European Academy of Neurology (EAN) guideline on the management of amyotrophic lateral sclerosis in collaboration with European Reference Network for Neuromuscular Diseases (ERN EURO-NMD).
European journal of neurology. 2024 Jun; 31(Jun):e16264. doi: 10.1111/ene.16264. pii: e16264. Base : PUBMED
- Atualizado em 21/08/2024

AAPM&R consensus guidance on spasticity assessment and management.
PM & R : the journal of injury, function, and rehabilitation. 2024 May; doi: 10.1002/pmrj.13211. pii: . Base : PUBMED
- Atualizado em 12/07/2024

Pediatric and Adult Brain Death/Death by Neurologic Criteria Consensus Guideline.
Neurology. 2023 Dec; 101(Dec):1112-1132. doi: 10.1212/WNL.0000000000207740. pii: . Base : PUBMED
- Atualizado em 16/05/2024

A Systematic Guideline by the ASPN Workgroup on the Evidence, Education, and Treatment Algorithm for Painful Diabetic Neuropathy: SWEET.
Journal of pain research. 2024 ; 17():1461-1501. doi: 10.2147/JPR.S451006. pii: . Base : PUBMED
- Atualizado em 22/04/2024

Pharmacological and neurosurgical management of cerebral palsy and dystonia: Clinical practice guideline update.
Developmental medicine and child neurology. 2024 Apr; doi: 10.1111/dmcn.15921. pii: . Base : PUBMED
- Atualizado em 22/04/2024

Guidelines of the International Headache Society for Controlled Clinical Trials in Idiopathic Intracranial Hypertension.
Cephalalgia : an international journal of headache. 2023 Aug; 43(Aug):3331024231197118. doi: 10.1177/03331024231197118. pii: . Base : PUBMED
- Atualizado em 19/04/2024

Current treatment options for cluster headache: limitations and the unmet need for better and specific treatments-a consensus article.
The journal of headache and pain. 2023 Sep; 24(Sep):121. doi: 10.1186/s10194-023-01660-8. pii: 121. Base : PUBMED
- Atualizado em 19/04/2024

European Academy of Neurology guidelines on the treatment of cluster headache.
European journal of neurology. 2023 Oct; 30(Oct):2955-2979. doi: 10.1111/ene.15956. pii: . Base : PUBMED
- Atualizado em 19/04/2024

European Academy of Neurology/Peripheral Nerve Society Guideline on diagnosis and treatment of Guillain-Barré syndrome.
European journal of neurology. 2023 Dec; 30(Dec):3646-3674. doi: 10.1111/ene.16073. pii: . Base : PUBMED
- Atualizado em 19/04/2024

ENA Clinical Practice Guideline Synopsis: Screening Older Adults for Cognitive Impairment.
Journal of emergency nursing. 2024 Jan; 50(Jan):17-21. doi: 10.1016/j.jen.2023.09.003. pii: S0099-1767(23)00244-1. Base : PUBMED
- Atualizado em 02/02/2024

Latin American consensus recommendations on the risk of infections in people with multiple sclerosis treated with disease modifying drugs.
Multiple sclerosis and related disorders. 2023 Sep; 77(Sep):104840. doi: 10.1016/j.msard.2023.104840. pii: S2211-0348(23)00342-5. Base : PUBMED
- Atualizado em 27/09/2023

Guidelines for Qualifications of Neurodiagnostic Personnel: A Joint Position Statement of the American Clinical Neurophysiology Society, the American Association of Neuromuscular & Electrodiagnostic Medicine, the American Society of Neurophysiological Monitoring, and ASET The Neurodiagnostic Society.
Muscle & nerve. 2023 Aug; 68(Aug):106-121. doi: 10.1002/mus.27850. pii: . Base : PUBMED
- Atualizado em 14/09/2023

Guidelines Update: Guidelines of the International Headache Society for controlled trials of preventive treatment of migraine in children and adolescents, 1st edition - An experience-based update.
Cephalalgia : an international journal of headache. 2023 May; 43(May):3331024231178239. doi: 10.1177/03331024231178239. pii: . Base : PUBMED
- Atualizado em 14/07/2023

Guidelines for the management of trigeminal neuralgia.
Cleveland Clinic journal of medicine. 2023 Jun; 90(Jun):355-362. doi: 10.3949/ccjm.90a.22052. pii: . Base : PUBMED
- Atualizado em 30/06/2023

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Ambient Air Pollution and the Severity of Alzheimer Disease Neuropathology.
JAMA neurology. 2025 Sep; doi: 10.1001/jamaneurol.2025.3316. pii: e253316. Base: PUBMED
- Atualizado em 17/09/2025

Neurosyphilis.
Annals of neurology. 2025 Sep; doi: 10.1002/ana.78016. pii: . Base: PUBMED
- Atualizado em 09/09/2025

Advances in the classification and management of idiopathic inflammatory myopathies.
The Lancet. Neurology. 2025 Sep; 24(Sep):776-788. doi: 10.1016/S1474-4422(25)00233-9. pii: S1474-4422(25)00233-9. Base: PUBMED
- Atualizado em 08/09/2025

Risdiplam in Presymptomatic Spinal Muscular Atrophy.
The New England journal of medicine. 2025 Aug; 393(Aug):671-682. doi: 10.1056/NEJMoa2410120. pii: . Base: PUBMED
- Atualizado em 04/09/2025

Posterior reversible encephalopathy syndrome: evolving insights in diagnosis, management, and outcomes.
The Lancet. Neurology. 2025 Sep; 24(Sep):789-800. doi: 10.1016/S1474-4422(25)00232-7. pii: S1474-4422(25)00232-7. Base: PUBMED
- Atualizado em 03/09/2025

Ictal Asystole During ECT.
The journal of ECT. 2025 Aug; doi: 10.1097/YCT.0000000000001178. pii: . Base: PUBMED
- Atualizado em 01/09/2025

Safety and efficacy of apitegromab in nonambulatory type 2 or type 3 spinal muscular atrophy (SAPPHIRE): a phase 3, double-blind, randomised, placebo-controlled trial.
The Lancet. Neurology. 2025 Sep; 24(Sep):727-739. doi: 10.1016/S1474-4422(25)00225-X. pii: S1474-4422(25)00225-X. Base: PUBMED
- Atualizado em 01/09/2025

Down syndrome and Alzheimer's disease: insights into biomarkers, clinical symptoms, and pathology.
The Lancet. Neurology. 2025 Sep; 24(Sep):753-762. doi: 10.1016/S1474-4422(25)00237-6. pii: S1474-4422(25)00237-6. Base: PUBMED
- Atualizado em 01/09/2025

MR Imaging versus Noncontrast CT for Selecting Patients with Acute Ischemic Stroke of Large Vessel Occlusion for Endovascular Thrombectomy: A Systematic Review and Meta-analysis.
AJNR. American journal of neuroradiology. 2025 Aug; doi: 10.3174/ajnr.A8775. pii: . Base: PUBMED
- Atualizado em 30/08/2025

Treatment Response to Antiseizure Medications in People With Newly Diagnosed Focal Epilepsy.
JAMA neurology. 2025 Aug; doi: 10.1001/jamaneurol.2025.2949. pii: e252949. Base: PUBMED
- Atualizado em 29/08/2025

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