Infectologia

Artigos em destaque

Guidance on the clinical management of HIV-1 persistent low-level viraemia on antiretroviral treatment: a scoping review and an international Delphi consensus.
The lancet. HIV. 2026 Jun; doi: 10.1016/S2352-3018(26)00107-4. pii: S2352-3018(26)00107-4. Base: PUBMED
- Atualizado em 20/07/2026

Post-pandemic impact on the epidemiology of invasive pneumococcal disease: consensus statement from the Latin American Society of Pediatric Infectious Diseases (SLIPE).
Expert review of vaccines. 2026 Dec; 25(Dec):2689604. doi: 10.1080/14760584.2026.2689604. pii: . Base: PUBMED
- Atualizado em 14/07/2026

British Society for Medical Mycology best practice recommendations for the diagnosis of serious fungal diseases: 2025 update.
The Lancet. Infectious diseases. 2026 Jun; 26(Jun):e217-e231. doi: 10.1016/S1473-3099(25)00550-X. pii: S1473-3099(25)00550-X. Base: PUBMED
- Atualizado em 10/07/2026

News e Reviews

Meningococcal B Vaccine to Prevent Neisseria gonorrhoeae Infection.
The New England journal of medicine. 2026 Jul; 395(Jul):349-361. doi: 10.1056/NEJMoa2516739. pii: . Base: PUBMED
- Atualizado em 24/07/2026

Phase 3 Results of Bepirovirsen Treatment for Chronic Hepatitis B Virus Infection.
The New England journal of medicine. 2026 Jun; 394(Jun):2395-2406. doi: 10.1056/NEJMoa2515131. pii: . Base: PUBMED
- Atualizado em 22/07/2026

Invasive Candidiasis in Critically Ill Patients: Fundamental Concepts and Future Directions.
Chest. 2026 Jun; 169(Jun):1561-1574. doi: 10.1016/j.chest.2025.12.020. pii: S0012-3692(25)05954-9. Base: PUBMED
- Atualizado em 22/07/2026

COVID-19 Vaccines for 2025-2026 in Adults Who Are Not Pregnant or Immunocompromised: Rapid Practice Points From the American College of Physicians.
Annals of internal medicine. 2026 May; 179(May):728-733. doi: 10.7326/ANNALS-25-05026. pii: . Base: PUBMED
- Atualizado em 22/07/2026

Chikungunya.
JAMA. 2026 Jul; 336(Jul):84. doi: 10.1001/jama.2026.6427. pii: . Base: PUBMED
- Atualizado em 20/07/2026

Clinical Characteristics of Patients Infected with Bundibugyo Virus, DRC 2026.
The New England journal of medicine. 2026 Jun; doi: 10.1056/NEJMc2608070. pii: . Base: PUBMED
- Atualizado em 20/07/2026

Bundibugyo Virus Disease in 2026 - Clinical and Public Health Responses.
The New England journal of medicine. 2026 Jul; 395(Jul):278-289. doi: 10.1056/NEJMra2607216. pii: . Base: PUBMED
- Atualizado em 17/07/2026

Advancing diagnostics for Chagas disease: key product characteristics and harmonized evaluation strategies - an expert meeting report.
BMC infectious diseases. 2026 Jun; 26(Jun):doi: 10.1186/s12879-026-13565-3. pii: 1160. Base: PUBMED
- Atualizado em 14/07/2026

Non-intravenous Amphotericin B: A Review of Localized Administration Routes.
Infectious diseases and therapy. 2026 Jun; 15(Jun):1607-1632. doi: 10.1007/s40121-026-01342-3. pii: . Base: PUBMED
- Atualizado em 14/07/2026

Infections Caused by Fusobacterium Species: Microbiology, Clinical Syndromes and Management: A Narrative Review.
Infectious diseases and therapy. 2026 Jun; 15(Jun):1633-1647. doi: 10.1007/s40121-026-01348-x. pii: . Base: PUBMED
- Atualizado em 14/07/2026

Advanced neuroimaging for central nervous system infections: when, where, how, and why?
Current opinion in infectious diseases. 2026 Jun; 39(Jun):263-271. doi: 10.1097/QCO.0000000000001191. pii: . Base: PUBMED
- Atualizado em 13/07/2026

Updates on diagnosis and management of parasitic infections of the central nervous system.
Current opinion in infectious diseases. 2026 Jun; 39(Jun):240-248. doi: 10.1097/QCO.0000000000001190. pii: . Base: PUBMED
- Atualizado em 13/07/2026

Complexities in evaluation and management of infectious myelopathies.
Current opinion in infectious diseases. 2026 Jun; 39(Jun):227-239. doi: 10.1097/QCO.0000000000001204. pii: . Base: PUBMED
- Atualizado em 13/07/2026

Neurological manifestations of respiratory viral infections.
Current opinion in infectious diseases. 2026 Jun; 39(Jun):218-226. doi: 10.1097/QCO.0000000000001189. pii: . Base: PUBMED
- Atualizado em 13/07/2026

Ischaemia in tuberculous meningitis: update on pathophysiology, clinical predictors and management.
Current opinion in infectious diseases. 2026 Jun; 39(Jun):179-188. doi: 10.1097/QCO.0000000000001194. pii: . Base: PUBMED
- Atualizado em 13/07/2026

Nipah virus infection: what clinicians need to know.
Le infezioni in medicina. 2026 ; 34():164-176. doi: 10.53854/liim-3402-6. pii: . Base: PUBMED
- Atualizado em 10/07/2026

Recommendations on the Diagnosis and Treatment of Tuberculosis Infection: SEPAR/SEIMC/Spanish Ministry of Health Consensus Statement.
Enfermedades infecciosas y microbiologia clinica (English ed.). 2026 ; 44():503037. doi: 10.1016/j.eimce.2025.503037. pii: S2529-993X(25)00224-2. Base: PUBMED
- Atualizado em 10/07/2026

Beta-lactam de-labelling as a core antimicrobial stewardship strategy in the era of the antimicrobial resistance pandemic: a narrative review.
Current opinion in allergy and clinical immunology. 2026 Aug; 26(Aug):294-299. doi: 10.1097/ACI.0000000000001179. pii: . Base: PUBMED
- Atualizado em 06/07/2026

Antifungal susceptibility testing across fungi: why MICs vary and methods diverge and what MIC can miss.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 2026 Mar; doi: 10.1016/j.cmi.2026.03.004. pii: S1198-743X(26)00111-4. Base: PUBMED
- Atualizado em 02/07/2026

Burden of Invasive Pneumococcal Disease and Community-Acquired Pneumonia in Adults: Significant Adverse Outcomes and Costs beyond Direct Treatment.
Infectious diseases and therapy. 2026 Jul; 15(Jul):1869-1891. doi: 10.1007/s40121-026-01357-w. pii: . Base: PUBMED
- Atualizado em 26/06/2026

A Major Step toward a Cure for Hepatitis B Infection.
The New England journal of medicine. 2026 Jun; 394(Jun):2471-2472. doi: 10.1056/NEJMe2605575. pii: . Base: PUBMED
- Atualizado em 26/06/2026

Efficacy and Safety of an mRNA Seasonal Influenza Vaccine in Adults.
The New England journal of medicine. 2026 May; 394(May):1803-1813. doi: 10.1056/NEJMoa2516491. pii: . Base: PUBMED
- Atualizado em 17/06/2026

Guideline, consenso e protocolo

2025 Clinical Practice Guideline Update by the Infectious Diseases Society of America on the Treatment and Management of COVID-19: Pemivibart for Pre-exposure Prophylaxis, Vilobelimab for Critical Illness, and Abatacept or Infliximab for Severe or Critical Illness.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2026 Jan; 81(Jan):i1-i5. doi: 10.1093/cid/ciaf424. pii: . Base : PUBMED
- Atualizado em 19/01/2026

2025 Clinical Practice Guideline Update by the Infectious Diseases Society of America on the Treatment and Management of COVID-19: Abatacept.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2026 Jan; 81(Jan):i17-i21. doi: 10.1093/cid/ciaf354. pii: . Base : PUBMED
- Atualizado em 17/01/2026

A clinical practice guideline for tuberculous meningitis.
The Lancet. Infectious diseases. 2025 Aug; doi: 10.1016/S1473-3099(25)00364-0. pii: S1473-3099(25)00364-0. Base : PUBMED
- Atualizado em 04/11/2025

Global guideline for the diagnosis and management of candidiasis: an initiative of the ECMM in cooperation with ISHAM and ASM.
The Lancet. Infectious diseases. 2025 May; 25(May):e280-e293. doi: 10.1016/S1473-3099(24)00749-7. pii: S1473-3099(24)00749-7. Base : PUBMED
- Atualizado em 10/06/2025

State of the art and the future of microbiome-based biomarkers: a multidisciplinary Delphi consensus.
The Lancet. Microbe. 2025 Feb; 6(Feb):100948. doi: 10.1016/j.lanmic.2024.07.011. pii: S2666-5247(24)00201-5. Base : PUBMED
- Atualizado em 29/04/2025

Antiretroviral Drugs for Treatment and Prevention of HIV in Adults: 2024 Recommendations of the International Antiviral Society-USA Panel.
JAMA. 2025 Feb; 333(Feb):609-628. doi: 10.1001/jama.2024.24543. pii: . Base : PUBMED
- Atualizado em 29/04/2025

Advancing the chemotherapy of tuberculous meningitis: a consensus view.
The Lancet. Infectious diseases. 2025 Jan; 25(Jan):e47-e58. doi: 10.1016/S1473-3099(24)00512-7. pii: S1473-3099(24)00512-7. Base : PUBMED
- Atualizado em 19/03/2025

Primary Care Guidance for Providers of Care for Persons With Human Immunodeficiency Virus: 2024 Update by the HIV Medicine Association of the Infectious Diseases Society of America.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2024 Oct; doi: 10.1093/cid/ciae479. pii: ciae479. Base : PUBMED
- Atualizado em 19/03/2025

Meningitis (bacterial) and meningococcal disease: recognition, diagnosis and management-summary of updated NICE guidance.
BMJ (Clinical research ed.). 2024 Nov; 387(Nov):q2452. doi: 10.1136/bmj.q2452. pii: . Base : PUBMED
- Atualizado em 13/03/2025

Piperacillin/Tazobactam Susceptibility Test Interpretive Criteria for Enterobacterales: Recommendations From the United States Committee on Antimicrobial Susceptibility Testing.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2024 Dec; 79(Dec):1354-1362. doi: 10.1093/cid/ciae328. pii: . Base : PUBMED
- Atualizado em 03/02/2025

European Society of Clinical Microbiology and Infectious Diseases/European Committee on infection control clinical guidelines on pre-operative decolonization and targeted prophylaxis in patients colonized by multidrug-resistant Gram-positive bacteria before surgery.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 2024 Dec; 30(Dec):1537-1550. doi: 10.1016/j.cmi.2024.07.012. pii: S1198-743X(24)00341-0. Base : PUBMED
- Atualizado em 03/02/2025

Hepatitis C Guidance 2023 Update: AASLD-IDSA Recommendations for Testing, Managing, and Treating Hepatitis C Virus Infection.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2023 May; doi: 10.1093/cid/ciad319. pii: ciad319. Base : PUBMED
- Atualizado em 08/01/2025

2024 Clinical Practice Guideline Update by the Infectious Diseases Society of America on Complicated Intra-abdominal Infections: Risk Assessment in Adults and Children.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2024 Oct; 79(Oct):S88-S93. doi: 10.1093/cid/ciae347. pii: . Base : PUBMED
- Atualizado em 18/12/2024

The inclusion of children and adolescents in tuberculosis diagnostic development and evaluation-a consensus statement.
The Lancet. Infectious diseases. 2024 Nov; 24(Nov):e688-e695. doi: 10.1016/S1473-3099(24)00339-6. pii: S1473-3099(24)00339-6. Base : PUBMED
- Atualizado em 17/12/2024

2024 Clinical Practice Guideline Update by the Infectious Diseases Society of America on Complicated Intra-abdominal Infections: Diagnostic Imaging of Suspected Acute Diverticulitis in Adults and Pregnant People.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2024 Oct; 79(Oct):S109-S112. doi: 10.1093/cid/ciae350. pii: . Base : PUBMED
- Atualizado em 17/12/2024

2024 Clinical Practice Guideline Update by the Infectious Diseases Society of America on Complicated Intraabdominal Infections: Diagnostic Imaging of Suspected Acute Cholecystitis and Acute Cholangitis in Adults, Children, and Pregnant People.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2024 Oct; 79(Oct):S104-S108. doi: 10.1093/cid/ciae349. pii: . Base : PUBMED
- Atualizado em 17/12/2024

2024 Clinical Practice Guideline Update by the Infectious Diseases Society of America on Complicated Intra-abdominal Infections: Diagnostic Imaging of Suspected Acute Appendicitis in Adults, Children, and Pregnant People.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2024 Oct; 79(Oct):S94-S103. doi: 10.1093/cid/ciae348. pii: . Base : PUBMED
- Atualizado em 17/12/2024

EASL Clinical Practice Guidelines on hepatitis delta virus.
Journal of hepatology. 2023 Aug; 79(Aug):433-460. doi: 10.1016/j.jhep.2023.05.001. pii: S0168-8278(23)00317-3. Base : PUBMED
- Atualizado em 11/12/2024

Global guideline for the diagnosis and management of cryptococcosis: an initiative of the ECMM and ISHAM in cooperation with the ASM.
The Lancet. Infectious diseases. 2024 Feb; doi: 10.1016/S1473-3099(23)00731-4. pii: S1473-3099(23)00731-4. Base : PUBMED
- Atualizado em 04/12/2024

A Review of Antibacterial Candidates with New Modes of Action.
ACS infectious diseases. 2024 Oct; 10(Oct):3440-3474. doi: 10.1021/acsinfecdis.4c00218. pii: . Base : PUBMED
- Atualizado em 26/11/2024

2024 Clinical Practice Guideline Update by the Infectious Diseases Society of America on Complicated Intra-abdominal Infections: Utility of Intra-abdominal Fluid Cultures in Adults, Children, and Pregnant People.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2024 Oct; 79(Oct):S123-S126. doi: 10.1093/cid/ciae353. pii: . Base : PUBMED
- Atualizado em 26/11/2024

2024 Clinical Practice Guideline Update by the Infectious Diseases Society of America on Complicated Intra-abdominal Infections: Utility of Blood Cultures in Adults, Children, and Pregnant People.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2024 Oct; 79(Oct):S118-S122. doi: 10.1093/cid/ciae352. pii: . Base : PUBMED
- Atualizado em 26/11/2024

2024 Clinical Practice Guideline Update by the Infectious Diseases Society of America on Complicated Intra-abdominal Infections: Risk Assessment, Diagnostic Imaging, and Microbiological Evaluation in Adults, Children, and Pregnant People.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2024 Oct; 79(Oct):S81-S87. doi: 10.1093/cid/ciae346. pii: . Base : PUBMED
- Atualizado em 26/11/2024

Consensus recommendations for use of long-acting antiretroviral medications in the treatment and prevention of HIV-1: Endorsed by the American Academy of HIV Medicine, American College of Clinical Pharmacy, Canadian HIV and Viral Hepatitis Pharmacists Network, European AIDS Clinical Society, and Society of Infectious Diseases Pharmacists.
Pharmacotherapy. 2024 Jul; 44(Jul):494-538. doi: 10.1002/phar.2922. pii: . Base : PUBMED
- Atualizado em 22/10/2024

Invasive Fungal Diseases in Adult Patients in Intensive Care Unit (FUNDICU): 2024 consensus definitions from ESGCIP, EFISG, ESICM, ECMM, MSGERC, ISAC, and ISHAM.
Intensive care medicine. 2024 Apr; 50(Apr):502-515. doi: 10.1007/s00134-024-07341-7. pii: . Base : PUBMED
- Atualizado em 17/07/2024

Clinical Practice Guideline by the Pediatric Infectious Diseases Society (PIDS) and the Infectious Diseases Society of America (IDSA): 2023 Guideline on Diagnosis and Management of Acute Bacterial Arthritis in Pediatrics.
Journal of the Pediatric Infectious Diseases Society. 2024 Jan; 13(Jan):1-59. doi: 10.1093/jpids/piad089. pii: . Base : PUBMED
- Atualizado em 16/05/2024

Infectious Diseases Society of America 2023 Guidance on the Treatment of Antimicrobial Resistant Gram-Negative Infections.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2023 Jul; doi: 10.1093/cid/ciad428. pii: ciad428. Base : PUBMED
- Atualizado em 27/02/2024

Screening for Latent Tuberculosis Infection in Adults: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force.
JAMA. 2023 May; 329(May):1495-1509. doi: 10.1001/jama.2023.3954. pii: . Base : PUBMED
- Atualizado em 07/02/2024

Guidelines for the management of norovirus outbreaks in acute and community health and social care settings.
The Journal of hospital infection. 2023 Jun; 136(Jun):127-191. doi: 10.1016/j.jhin.2023.01.017. pii: S0195-6701(23)00043-9. Base : PUBMED
- Atualizado em 06/06/2023

AACC Guidance Document on the Clinical Use of Procalcitonin.
The journal of applied laboratory medicine. 2023 May; 8(May):598-634. doi: 10.1093/jalm/jfad007. pii: . Base : PUBMED
- Atualizado em 08/05/2023

Infectious Diseases Society of America Guidance on the Treatment of AmpC β-Lactamase-Producing Enterobacterales, Carbapenem-Resistant Acinetobacter baumannii, and Stenotrophomonas maltophilia Infections.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2022 07; 74(07):2089-2114. doi: 10.1093/cid/ciab1013. pii: . Base : PUBMED
- Atualizado em 22/03/2023

Clinical Practice Guideline by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA): 2021 Focused Update Guidelines on Management of Clostridioides difficile Infection in Adults.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2021 09; 73(09):e1029-e1044. doi: 10.1093/cid/ciab549. pii: . Base : PUBMED
- Atualizado em 09/08/2022

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Rabies Despite Postexposure Prophylaxis in High-Burden Settings: Vaccine Failure or Gaps in Healthcare Delivery?
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2026 Jul; 83(Jul):139-146. doi: 10.1093/cid/ciaf662. pii: . Base: PUBMED
- Atualizado em 24/07/2026

Meningococcal B Vaccine to Prevent Neisseria gonorrhoeae Infection.
The New England journal of medicine. 2026 Jul; 395(Jul):349-361. doi: 10.1056/NEJMoa2516739. pii: . Base: PUBMED
- Atualizado em 24/07/2026

Phase 3 Results of Bepirovirsen Treatment for Chronic Hepatitis B Virus Infection.
The New England journal of medicine. 2026 Jun; 394(Jun):2395-2406. doi: 10.1056/NEJMoa2515131. pii: . Base: PUBMED
- Atualizado em 22/07/2026

Chikungunya.
JAMA. 2026 Jul; 336(Jul):84. doi: 10.1001/jama.2026.6427. pii: . Base: PUBMED
- Atualizado em 20/07/2026

Clinical Characteristics of Patients Infected with Bundibugyo Virus, DRC 2026.
The New England journal of medicine. 2026 Jun; doi: 10.1056/NEJMc2608070. pii: . Base: PUBMED
- Atualizado em 20/07/2026

Bundibugyo Virus Disease in 2026 - Clinical and Public Health Responses.
The New England journal of medicine. 2026 Jul; 395(Jul):278-289. doi: 10.1056/NEJMra2607216. pii: . Base: PUBMED
- Atualizado em 17/07/2026

Advancing diagnostics for Chagas disease: key product characteristics and harmonized evaluation strategies - an expert meeting report.
BMC infectious diseases. 2026 Jun; 26(Jun):doi: 10.1186/s12879-026-13565-3. pii: 1160. Base: PUBMED
- Atualizado em 14/07/2026

Long-Acting Treatment and Advanced HIV Disease - Addressing a Public Health Priority.
The New England journal of medicine. 2026 Jun; doi: 10.1056/NEJMp2605547. pii: . Base: PUBMED
- Atualizado em 02/07/2026

Burden of Invasive Pneumococcal Disease and Community-Acquired Pneumonia in Adults: Significant Adverse Outcomes and Costs beyond Direct Treatment.
Infectious diseases and therapy. 2026 Jul; 15(Jul):1869-1891. doi: 10.1007/s40121-026-01357-w. pii: . Base: PUBMED
- Atualizado em 26/06/2026

A Major Step toward a Cure for Hepatitis B Infection.
The New England journal of medicine. 2026 Jun; 394(Jun):2471-2472. doi: 10.1056/NEJMe2605575. pii: . Base: PUBMED
- Atualizado em 26/06/2026