Infectologia

Artigos em destaque

State-of-the-Art Review: Infectious Diarrhea.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2025 Dec; 81(Dec):e250-e262. doi: 10.1093/cid/ciaf356. pii: . Base: PUBMED
- Atualizado em 09/01/2026

Trial of High-Dose Oral Rifampin in Adults with Tuberculous Meningitis.
The New England journal of medicine. 2025 Dec; 393(Dec):2434-2446. doi: 10.1056/NEJMoa2502866. pii: . Base: PUBMED
- Atualizado em 19/12/2025

Innovations in the biomedical prevention, diagnosis, and service delivery of HIV and other sexually transmitted infections.
Lancet (London, England). 2025 Nov; 406(Nov):2133-2151. doi: 10.1016/S0140-6736(25)00983-3. pii: S0140-6736(25)00983-3. Base: PUBMED
- Atualizado em 05/12/2025

News e Reviews

Molecular diagnostics for infectious disease.
Clinica chimica acta; international journal of clinical chemistry. 2026 Jan; 579(Jan):120619. doi: 10.1016/j.cca.2025.120619. pii: S0009-8981(25)00498-X. Base: PUBMED
- Atualizado em 16/01/2026

New COVID-19 Vaccination Guidelines for Immunocompromised Individuals.
JAMA. 2025 Dec; 334(Dec):1971. doi: 10.1001/jama.2025.19727. pii: . Base: PUBMED
- Atualizado em 12/01/2026

Efficacy, Immunogenicity, and Safety of Modified mRNA Influenza Vaccine.
The New England journal of medicine. 2025 Nov; 393(Nov):2001-2011. doi: 10.1056/NEJMoa2416779. pii: . Base: PUBMED
- Atualizado em 07/01/2026

Management of Severe Clostridioides difficile Infection.
Infectious disease clinics of North America. 2025 Dec; 39(Dec):653-662. doi: 10.1016/j.idc.2025.07.006. pii: S0891-5520(25)00069-8. Base: PUBMED
- Atualizado em 19/12/2025

Immune Aspects of Clostridioides difficile Infection and Vaccine Development.
Infectious disease clinics of North America. 2025 Dec; 39(Dec):801-820. doi: 10.1016/j.idc.2025.07.008. pii: S0891-5520(25)00071-6. Base: PUBMED
- Atualizado em 19/12/2025

Characterization of Serotype-Specific Dengue Virus T-Cell Inhibition.
The Journal of infectious diseases. 2025 Nov; 232(Nov):1228-1238. doi: 10.1093/infdis/jiaf241. pii: . Base: PUBMED
- Atualizado em 19/12/2025

Host Immune Response Profiling for the Diagnosis of Infectious Diseases.
The Journal of infectious diseases. 2025 Nov; 232(Nov):1029-1039. doi: 10.1093/infdis/jiaf428. pii: . Base: PUBMED
- Atualizado em 19/12/2025

Immune Correlates and Vaccine Immunobridging: Statistical Innovations, Challenges, and Opportunities.
The Journal of infectious diseases. 2025 Nov; 232(Nov):1024-1028. doi: 10.1093/infdis/jiaf451. pii: . Base: PUBMED
- Atualizado em 19/12/2025

Management of individuals exposed to multidrug-resistant or rifampicin-resistant tuberculosis.
The Lancet. Infectious diseases. 2025 Dec; 25(Dec):e692-e704. doi: 10.1016/S1473-3099(25)00157-4. pii: S1473-3099(25)00157-4. Base: PUBMED
- Atualizado em 19/12/2025

Updated Evidence for Covid-19, RSV, and Influenza Vaccines for 2025-2026.
The New England journal of medicine. 2025 Dec; 393(Dec):2221-2242. doi: 10.1056/NEJMsa2514268. pii: . Base: PUBMED
- Atualizado em 19/12/2025

A Pragmatic Trial of Glucocorticoids for Community-Acquired Pneumonia.
The New England journal of medicine. 2025 Dec; 393(Dec):2187-2197. doi: 10.1056/NEJMoa2507100. pii: . Base: PUBMED
- Atualizado em 19/12/2025

Neurological Events Associated With Acute Dengue Infection.
JAMA neurology. 2025 Nov; doi: 10.1001/jamaneurol.2025.4608. pii: e254608. Base: PUBMED
- Atualizado em 18/12/2025

Shigellosis.
Lancet (London, England). 2025 Oct; 406(Oct):1508-1519. doi: 10.1016/S0140-6736(25)01033-5. pii: S0140-6736(25)01033-5. Base: PUBMED
- Atualizado em 17/12/2025

Rabies Despite Post-Exposure Prophylaxis in High-Burden Settings: Vaccine Failure or Gaps in Healthcare Delivery?
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2025 Dec; doi: 10.1093/cid/ciaf662. pii: ciaf662. Base: PUBMED
- Atualizado em 15/12/2025

Viral Infections Associated With Injection Drug Use.
JAMA. 2025 Oct; 334(Oct):1386-1387. doi: 10.1001/jama.2025.13287. pii: . Base: PUBMED
- Atualizado em 10/12/2025

Mannose Derivatives as Anti-Infective Agents.
International journal of molecular sciences. 2025 Oct; 26(Oct):doi: 10.3390/ijms262010230. pii: 10230. Base: PUBMED
- Atualizado em 05/12/2025

Structural and Functional Insights into Viral and Fungal Proteins Involved in Chronic Inflammation and Their Biologic Treatments.
Pharmaceutics. 2025 Nov; 17(Nov):doi: 10.3390/pharmaceutics17111466. pii: 1466. Base: PUBMED
- Atualizado em 05/12/2025

Syphilis: A Review.
JAMA. 2025 Dec; 334(Dec):1927-1940. doi: 10.1001/jama.2025.17362. pii: . Base: PUBMED
- Atualizado em 03/12/2025

Guideline, consenso e protocolo

2025 Clinical Practice Guideline Update by the Infectious Diseases Society of America on the Treatment and Management of COVID-19: Pemivibart for Pre-exposure Prophylaxis, Vilobelimab for Critical Illness, and Abatacept or Infliximab for Severe or Critical Illness.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2026 Jan; 81(Jan):i1-i5. doi: 10.1093/cid/ciaf424. pii: . Base : PUBMED
- Atualizado em 19/01/2026

2025 Clinical Practice Guideline Update by the Infectious Diseases Society of America on the Treatment and Management of COVID-19: Abatacept.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2026 Jan; 81(Jan):i17-i21. doi: 10.1093/cid/ciaf354. pii: . Base : PUBMED
- Atualizado em 17/01/2026

A clinical practice guideline for tuberculous meningitis.
The Lancet. Infectious diseases. 2025 Aug; doi: 10.1016/S1473-3099(25)00364-0. pii: S1473-3099(25)00364-0. Base : PUBMED
- Atualizado em 04/11/2025

Global guideline for the diagnosis and management of candidiasis: an initiative of the ECMM in cooperation with ISHAM and ASM.
The Lancet. Infectious diseases. 2025 May; 25(May):e280-e293. doi: 10.1016/S1473-3099(24)00749-7. pii: S1473-3099(24)00749-7. Base : PUBMED
- Atualizado em 10/06/2025

State of the art and the future of microbiome-based biomarkers: a multidisciplinary Delphi consensus.
The Lancet. Microbe. 2025 Feb; 6(Feb):100948. doi: 10.1016/j.lanmic.2024.07.011. pii: S2666-5247(24)00201-5. Base : PUBMED
- Atualizado em 29/04/2025

Antiretroviral Drugs for Treatment and Prevention of HIV in Adults: 2024 Recommendations of the International Antiviral Society-USA Panel.
JAMA. 2025 Feb; 333(Feb):609-628. doi: 10.1001/jama.2024.24543. pii: . Base : PUBMED
- Atualizado em 29/04/2025

Advancing the chemotherapy of tuberculous meningitis: a consensus view.
The Lancet. Infectious diseases. 2025 Jan; 25(Jan):e47-e58. doi: 10.1016/S1473-3099(24)00512-7. pii: S1473-3099(24)00512-7. Base : PUBMED
- Atualizado em 19/03/2025

Primary Care Guidance for Providers of Care for Persons With Human Immunodeficiency Virus: 2024 Update by the HIV Medicine Association of the Infectious Diseases Society of America.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2024 Oct; doi: 10.1093/cid/ciae479. pii: ciae479. Base : PUBMED
- Atualizado em 19/03/2025

Meningitis (bacterial) and meningococcal disease: recognition, diagnosis and management-summary of updated NICE guidance.
BMJ (Clinical research ed.). 2024 Nov; 387(Nov):q2452. doi: 10.1136/bmj.q2452. pii: . Base : PUBMED
- Atualizado em 13/03/2025

Piperacillin/Tazobactam Susceptibility Test Interpretive Criteria for Enterobacterales: Recommendations From the United States Committee on Antimicrobial Susceptibility Testing.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2024 Dec; 79(Dec):1354-1362. doi: 10.1093/cid/ciae328. pii: . Base : PUBMED
- Atualizado em 03/02/2025

European Society of Clinical Microbiology and Infectious Diseases/European Committee on infection control clinical guidelines on pre-operative decolonization and targeted prophylaxis in patients colonized by multidrug-resistant Gram-positive bacteria before surgery.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 2024 Dec; 30(Dec):1537-1550. doi: 10.1016/j.cmi.2024.07.012. pii: S1198-743X(24)00341-0. Base : PUBMED
- Atualizado em 03/02/2025

Hepatitis C Guidance 2023 Update: AASLD-IDSA Recommendations for Testing, Managing, and Treating Hepatitis C Virus Infection.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2023 May; doi: 10.1093/cid/ciad319. pii: ciad319. Base : PUBMED
- Atualizado em 08/01/2025

2024 Clinical Practice Guideline Update by the Infectious Diseases Society of America on Complicated Intra-abdominal Infections: Risk Assessment in Adults and Children.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2024 Oct; 79(Oct):S88-S93. doi: 10.1093/cid/ciae347. pii: . Base : PUBMED
- Atualizado em 18/12/2024

The inclusion of children and adolescents in tuberculosis diagnostic development and evaluation-a consensus statement.
The Lancet. Infectious diseases. 2024 Nov; 24(Nov):e688-e695. doi: 10.1016/S1473-3099(24)00339-6. pii: S1473-3099(24)00339-6. Base : PUBMED
- Atualizado em 17/12/2024

2024 Clinical Practice Guideline Update by the Infectious Diseases Society of America on Complicated Intra-abdominal Infections: Diagnostic Imaging of Suspected Acute Diverticulitis in Adults and Pregnant People.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2024 Oct; 79(Oct):S109-S112. doi: 10.1093/cid/ciae350. pii: . Base : PUBMED
- Atualizado em 17/12/2024

2024 Clinical Practice Guideline Update by the Infectious Diseases Society of America on Complicated Intraabdominal Infections: Diagnostic Imaging of Suspected Acute Cholecystitis and Acute Cholangitis in Adults, Children, and Pregnant People.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2024 Oct; 79(Oct):S104-S108. doi: 10.1093/cid/ciae349. pii: . Base : PUBMED
- Atualizado em 17/12/2024

2024 Clinical Practice Guideline Update by the Infectious Diseases Society of America on Complicated Intra-abdominal Infections: Diagnostic Imaging of Suspected Acute Appendicitis in Adults, Children, and Pregnant People.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2024 Oct; 79(Oct):S94-S103. doi: 10.1093/cid/ciae348. pii: . Base : PUBMED
- Atualizado em 17/12/2024

EASL Clinical Practice Guidelines on hepatitis delta virus.
Journal of hepatology. 2023 Aug; 79(Aug):433-460. doi: 10.1016/j.jhep.2023.05.001. pii: S0168-8278(23)00317-3. Base : PUBMED
- Atualizado em 11/12/2024

Global guideline for the diagnosis and management of cryptococcosis: an initiative of the ECMM and ISHAM in cooperation with the ASM.
The Lancet. Infectious diseases. 2024 Feb; doi: 10.1016/S1473-3099(23)00731-4. pii: S1473-3099(23)00731-4. Base : PUBMED
- Atualizado em 04/12/2024

A Review of Antibacterial Candidates with New Modes of Action.
ACS infectious diseases. 2024 Oct; 10(Oct):3440-3474. doi: 10.1021/acsinfecdis.4c00218. pii: . Base : PUBMED
- Atualizado em 26/11/2024

2024 Clinical Practice Guideline Update by the Infectious Diseases Society of America on Complicated Intra-abdominal Infections: Utility of Intra-abdominal Fluid Cultures in Adults, Children, and Pregnant People.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2024 Oct; 79(Oct):S123-S126. doi: 10.1093/cid/ciae353. pii: . Base : PUBMED
- Atualizado em 26/11/2024

2024 Clinical Practice Guideline Update by the Infectious Diseases Society of America on Complicated Intra-abdominal Infections: Utility of Blood Cultures in Adults, Children, and Pregnant People.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2024 Oct; 79(Oct):S118-S122. doi: 10.1093/cid/ciae352. pii: . Base : PUBMED
- Atualizado em 26/11/2024

2024 Clinical Practice Guideline Update by the Infectious Diseases Society of America on Complicated Intra-abdominal Infections: Risk Assessment, Diagnostic Imaging, and Microbiological Evaluation in Adults, Children, and Pregnant People.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2024 Oct; 79(Oct):S81-S87. doi: 10.1093/cid/ciae346. pii: . Base : PUBMED
- Atualizado em 26/11/2024

Consensus recommendations for use of long-acting antiretroviral medications in the treatment and prevention of HIV-1: Endorsed by the American Academy of HIV Medicine, American College of Clinical Pharmacy, Canadian HIV and Viral Hepatitis Pharmacists Network, European AIDS Clinical Society, and Society of Infectious Diseases Pharmacists.
Pharmacotherapy. 2024 Jul; 44(Jul):494-538. doi: 10.1002/phar.2922. pii: . Base : PUBMED
- Atualizado em 22/10/2024

Invasive Fungal Diseases in Adult Patients in Intensive Care Unit (FUNDICU): 2024 consensus definitions from ESGCIP, EFISG, ESICM, ECMM, MSGERC, ISAC, and ISHAM.
Intensive care medicine. 2024 Apr; 50(Apr):502-515. doi: 10.1007/s00134-024-07341-7. pii: . Base : PUBMED
- Atualizado em 17/07/2024

Clinical Practice Guideline by the Pediatric Infectious Diseases Society (PIDS) and the Infectious Diseases Society of America (IDSA): 2023 Guideline on Diagnosis and Management of Acute Bacterial Arthritis in Pediatrics.
Journal of the Pediatric Infectious Diseases Society. 2024 Jan; 13(Jan):1-59. doi: 10.1093/jpids/piad089. pii: . Base : PUBMED
- Atualizado em 16/05/2024

Infectious Diseases Society of America 2023 Guidance on the Treatment of Antimicrobial Resistant Gram-Negative Infections.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2023 Jul; doi: 10.1093/cid/ciad428. pii: ciad428. Base : PUBMED
- Atualizado em 27/02/2024

Screening for Latent Tuberculosis Infection in Adults: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force.
JAMA. 2023 May; 329(May):1495-1509. doi: 10.1001/jama.2023.3954. pii: . Base : PUBMED
- Atualizado em 07/02/2024

Guidelines for the management of norovirus outbreaks in acute and community health and social care settings.
The Journal of hospital infection. 2023 Jun; 136(Jun):127-191. doi: 10.1016/j.jhin.2023.01.017. pii: S0195-6701(23)00043-9. Base : PUBMED
- Atualizado em 06/06/2023

AACC Guidance Document on the Clinical Use of Procalcitonin.
The journal of applied laboratory medicine. 2023 May; 8(May):598-634. doi: 10.1093/jalm/jfad007. pii: . Base : PUBMED
- Atualizado em 08/05/2023

Infectious Diseases Society of America Guidance on the Treatment of AmpC β-Lactamase-Producing Enterobacterales, Carbapenem-Resistant Acinetobacter baumannii, and Stenotrophomonas maltophilia Infections.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2022 07; 74(07):2089-2114. doi: 10.1093/cid/ciab1013. pii: . Base : PUBMED
- Atualizado em 22/03/2023

Clinical Practice Guideline by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA): 2021 Focused Update Guidelines on Management of Clostridioides difficile Infection in Adults.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2021 09; 73(09):e1029-e1044. doi: 10.1093/cid/ciab549. pii: . Base : PUBMED
- Atualizado em 09/08/2022

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2025 Clinical Practice Guideline Update by the Infectious Diseases Society of America on the Treatment and Management of COVID-19: Pemivibart for Pre-exposure Prophylaxis, Vilobelimab for Critical Illness, and Abatacept or Infliximab for Severe or Critical Illness.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2026 Jan; 81(Jan):i1-i5. doi: 10.1093/cid/ciaf424. pii: . Base: PUBMED
- Atualizado em 19/01/2026

2025 Clinical Practice Guideline Update by the Infectious Diseases Society of America on the Treatment and Management of COVID-19: Abatacept.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2026 Jan; 81(Jan):i17-i21. doi: 10.1093/cid/ciaf354. pii: . Base: PUBMED
- Atualizado em 17/01/2026

Molecular diagnostics for infectious disease.
Clinica chimica acta; international journal of clinical chemistry. 2026 Jan; 579(Jan):120619. doi: 10.1016/j.cca.2025.120619. pii: S0009-8981(25)00498-X. Base: PUBMED
- Atualizado em 16/01/2026

New COVID-19 Vaccination Guidelines for Immunocompromised Individuals.
JAMA. 2025 Dec; 334(Dec):1971. doi: 10.1001/jama.2025.19727. pii: . Base: PUBMED
- Atualizado em 12/01/2026

State-of-the-Art Review: Infectious Diarrhea.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2025 Dec; 81(Dec):e250-e262. doi: 10.1093/cid/ciaf356. pii: . Base: PUBMED
- Atualizado em 09/01/2026

Measles 2025.
The New England journal of medicine. 2025 Dec; 393(Dec):2447-2458. doi: 10.1056/NEJMra2504516. pii: . Base: PUBMED
- Atualizado em 06/01/2026

Trial of High-Dose Oral Rifampin in Adults with Tuberculous Meningitis.
The New England journal of medicine. 2025 Dec; 393(Dec):2434-2446. doi: 10.1056/NEJMoa2502866. pii: . Base: PUBMED
- Atualizado em 19/12/2025

Updated Evidence for Covid-19, RSV, and Influenza Vaccines for 2025-2026.
The New England journal of medicine. 2025 Dec; 393(Dec):2221-2242. doi: 10.1056/NEJMsa2514268. pii: . Base: PUBMED
- Atualizado em 19/12/2025

Rabies Despite Post-Exposure Prophylaxis in High-Burden Settings: Vaccine Failure or Gaps in Healthcare Delivery?
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2025 Dec; doi: 10.1093/cid/ciaf662. pii: ciaf662. Base: PUBMED
- Atualizado em 15/12/2025

High-Dose Influenza Vaccine to Reduce Hospitalizations.
The New England journal of medicine. 2025 Dec; 393(Dec):2303-2312. doi: 10.1056/NEJMoa2509834. pii: . Base: PUBMED
- Atualizado em 12/12/2025